ISA Pharmaceuticals

Publications

  • Success or failure of vaccination for HPV16-positive vulvar lesions correlates with kinetics and phenotype of induced T-cell responses  
    Marij J. P. Welters, Gemma G. Kenter, Peggy J. de Vos van Steenwijk, Margriet J. G. Löwik, Dorien M. A. Berends-van der Meer, Farah Essahsah, Linda F. M. Stynenbosch, Annelies P. G. Vloon, Tamara H. Ramwadhdoebe, Sytse J. Piersma, Jeanette M. van der Hulst, A. Rob P. M. Valentijn, Lorraine M. Fathers, Jan W. Drijfhout, Kees L. M. C. Franken, Jaap Oostendorp, Gert Jan Fleuren, Cornelis J. M. Melief, and Sjoerd H. van der Burg.
    2010, PNAS June 14, 2010

  • Vaccination against HPV-16 Oncoproteins for Vulvar Intraepithelial Neoplasia 
    Gemma G. Kenter, M.D., Ph.D., Marij J.P. Welters, Ph.D., A. Rob P.M. Valentijn, Ph.D., Margriet J.G. Lowik, Dorien M.A. Berends-van der Meer, Annelies P.G. Vloon, Farah Essahsah, Lorraine M. Fathers, Rienk Offringa, Ph.D., Jan Wouter Drijfhout, Ph.D., Amon R. Wafelman, Ph.D., Jaap Oostendorp, Ph.D., Gert Jan Fleuren, M.D., Ph.D., Sjoerd H. van der Burg, Ph.D., and Cornelis J.M. Melief, M.D., Ph.D..
    2009, New England Journal of Medicine November 5th, 2009, Volume 361:1838-1847

  • Induction of tumor-specific CD4+ and CD8+ T-cell immunity in cervical cancer patients by a human papillomavirus Type 16 E6 andE7 long peptides vaccine. 
    MJP Welters, GG Kenter, SJ Piersma, AP Vloon, MJ Lowik, DM Bernds- van der Meer, JW Drijfhout, AR Valentijn, AM Wafelman, J Oostendorp, GJ Fleuren, R Offringa, CJ Melief, SH van der Burg.
    2008, Clinical Cancer Research 14(1); 178-87

  • Phase I immunotherapeutic trial with long peptides spanning the E6 and E7 sequences of high risk human papilloma virus in end stage cervical cancer patients shows low toxicity and robust immunogenicity. 
    GG Kenter, MJ Welters, AR Valentijn, MJ Lowik, DM Berends-van der Meer, AP Vloon, JW Drijfhout, AR Wafelman, J Oostendorp, GJ Fleuren, R Offringa, SH van der Burg, CJM Melief..
    2008, Clinical Cancer Research 14(1); 169-77.

  • Cancer Immunotherapy by Dendritic Cells. 
    C.J.M. Melief..
    2008, Immunity 29, 19; 272-383.

  • Immunotherapy of Established (pre)malignant Disease by Synthetic Long Peptide Vaccines. 
    CJM Melief, SH van der Burg.
    2008, Nature Reviews Cancer  (8); 1-11

  • Therapeutic vaccines in cancer. 
    SH van der Burg.
    2008, Exp Rev Vaccines 7,(1):1-5.

  • Improved peptide vaccine strategies, creating synthetic artificial infections to maximize immune efficacy. 
    SH van der Burg, MS Bijker, MJP Welters, R Offringa, CJM Melief.
    2006, Adv Drug Del Rev 58:916-30